Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0003rdr33 | Environmental and Metabolic Interactions | REDR1994

Nutritional influences on reproduction in mature male sheep and goats

Martin GB , Walkden-Brown SW

Changes in the nutrition of mature rams and goat bucks lead to profound responses in testicular size and therefore the rate of production of spermatozoa. These effects are largely due to changes in the size of the seminiferous tubules and in the efficiency of spermatogenesis. With the exception of severe undernutrition, the effects on spermatogenic function are not accompanied by similar changes in endocrine function of the testes, as measured by the production of testosterone...

bp0004rdr19 | Male Function and Fertility | REDR1998

Role of male–female interaction in regulating reproduction in sheep and goats

Walkden-Brown SW , Martin GB , Restall BJ

The induction of synchronous ovulatory activity in anovulatory sheep and goats after the introduction of males, the 'male effect', has probably been used to advantage since these species were domesticated and the underlying physiological and behavioural mechanisms have been progressively elucidated over the past 50 years. Less well understood is the analogous effect of oestrous females on males. This review examines the nature and importance of these male–female i...

bp0005rdr29 | Nutrition-Reproduction Interactions | REDR2002

Fertility in male sheep: modulators of the acute effects of nutrition on the reproductive axis of male sheep

Blache D , Zhang S , Martin GB

Animals adjust the time of year that they reproduce through their ability to perceive and respond to critical aspects of their environment, such as photoperiod, nutrition or the socio–sexual milieu, and their genotype determines the degree of response to each stimulus. Ultimately, information from environmental cues filters through to the GnRH neurones in the brain which are the primary regulator of fertility. Each of these cues has been studied in isolation and the mech...

bp0006rdr8 | Nueroendocrinology | REDR2006

Nutritional inputs into the reproductive neuroendocrine control system - a multidimensional perspective

Blache D , Chagas LM , Martin GB

Evolution has shaped regulatory systems to improve the chance of reproductive success in a somewhat unpredictable environment. One of the more powerful regulators of reproductive function in both sexes is metabolic status, defined as the availability of nutrients and energy to the tissues. Here, we briefly review the basics of the relationship between metabolic status and the activity of the system that controls pulsatile GnRH and LH secretion. We then reflect on these relatio...

bp0003rdr22 | Regulation of Gonadotrophin Secretion | REDR1994

Dopaminergic control of LH secretion by the Al5 nucleus in anoestrous ewes

Thiery JC , Gayrard V , Le Corre S , Viguié C , Martin GB , Chemineau P , Malpaux B

Annual variations in the secretion of LH are responsible for seasonal changes in ovulatory activity in ewes. This hormonal pattern reflects an increase in the intensity of the negative feedback exerted by oestradiol under long days. Neuro-pharmacological studies have shown that this inhibition of LH secretion involves activation of catecholaminergic systems from preoptic and mediobasal hypothalamus (MBH) by oestradiol during anoestrus, and that 5-hydroxytryptamine inputs may a...