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Control of Pig Reproduction VIII

Control of Pig Reproduction VIII

State-of-The Art in Conceptus-Uterus Interactions/Early Pregnancy Signaling

bp0018cpr36 | State-of-The Art in Conceptus-Uterus Interactions/Early Pregnancy Signaling | CPR2009

Antiluteolytic mechanisms and the establishment of pregnancy in the pig

Waclawik A. , Blitek A. , Kaczmarek M.M. , Kiewisz J. , Ziecik A.J.

Extended exposure of progesterone and conceptus estrogen influences the vascular compartment of the uterus and expression of many factors, such as prostaglandins (PGs), growth factors, extracellular matrix and adhesion molecules, cytokines and transcription factors. One of the supportive mechanisms by which the conceptus inhibits luteolysis is by changing PG synthesis in favor of luteoprotective PGE2. Alteration in PG synthesis may result from increased PGE synthase (mPG...

bp0018cpr37 | State-of-The Art in Conceptus-Uterus Interactions/Early Pregnancy Signaling | CPR2009

Conceptus-uterus interactions in pigs: endometrial gene expression in response to estrogens and interferons from conceptuses

Johnson G.A. , Bazer F.W. , Burghardt R.C. , Spencer T.E. , Wu G. , Bayless K.J.

This review highlights information on conceptus-uterus interactions in the pig with respect to uterine gene expression in response to estrogens and interferons (IF Ns) secreted from elongating conceptuses. Pig conceptuses release estrogens for pregnancy recognition, but also secrete IENs that do not appear to be antiluteolytic. Estrogens and IFNs induce expression of largely non-overlapping sets of genes, and evidence suggests that pig conceptuses orchestrate essential e...