Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0003rdr12 | Development of the Reproductive Axis | REDR1994

Ontogeny of GnRH systems

Caldani1 M , Antoine M , Batailler M , Duittoz A

In all vertebrate species studied, the main central population of GnRH neurones, which produces the final messages regulating reproduction, originates outside the brain. Early during fetal life, they appear in the olfactory placode epithelium and then migrate toward the base of the telencephalon in close association with the nervus terminalis, penetrate the brain within the nervus terminalis roots, reach their final locations and eventually grow axons toward their targets. Onl...

bp0003rdr4 | Maternal-Embryo Interactions | REDR1994

Cellular interactions during implantation in domestic ruminants

Guillomot M

Implantation is a critical step in the progress of pregnancy, during which the conceptus acquires a fixed position within the uterine lumen, and leads to the establishment of the placental structures. This process implies some cellular modifications of both the uterine epithelium and the trophoblast to ensure cell adhesion between the two tissues. In ruminants, the implantation process is characterized by three main steps: a long pre-attachment period lasting 2–3 weeks d...

bp0001redr5 | (1) | REDR1980

Endocrine control of spermatogenesis in the ram

Courot M , Ortavant R

Summary. In the ram, the size of the testes is related to the concentrations of FSH, LH and testosterone in the blood. A significant linear relationship is observed between testicular size and the level of FSH until a maximum after which no further increase in testis size is observed. Testicular size is also linearly related to the mean level (25 consecutive hours of sampling) of LH and testosterone in the blood, with apparently no upper limit, and to the freq...

bp0008rdr27 | Placentation/Parturition | REDR2014

Evolution of placental structure and function in ruminants

Carter Anthony M

Summary. The defining feature of ruminant placentation is the fusion of binucleate trophoblast cells with uterine epithelium. It was present in the last common ancestor of ruminants and the fusion process is facilitated by the products of endogenous retroviral genes called syncytins. It provides a mechanism to transfer placental hormones to maternal tissues. One of these hormones is placental lactogen, which likewise was present in the ancestral ruminant. An i...

bp0009rdr15 | (1) | REDR1986

Function of the hypothalamic–hypophysial axis during the post-partum period in ewes and cows

Nett T. M.

Summary. During pregnancy the hypothalamic–hypophysial axis is suppressed by the high concentrations of progesterone and oestradiol in the circulation. The high concentrations of these steroids appear to inhibit secretion of GnRH from the hypothalamus, resulting in inadequate stimulation of pituitary gonadotrophs to maintain synthesis of LH. This produces a depletion of LH in the anterior pituitary gland that must be restored after parturition before nor...

bp0015cpr3 | Regulation of Reproductive Function | CPR1997

Control of follicular development and ovulation rate in pigs

Cox Nancy M. ,

There is considerable evidence that nutritional and metabolic control of follicular growth is mediated by metabolic hormones and growth factors, particularly with processes mediated by insulin-like growth factor I (IGF-I) and its binding proteins (IGFBPs). From knowledge that hormones and growth factors which can be affected by diet also positively affect ovarian function, the concept has emerged that metabolic modifiers of gonadotrophin action, rather than gonadotrophins...

bp0005rdr23 | Neuroendocrine Interactions | REDR2002

Origin of cerebrospinal fluid melatonin and possible function in the integration of photoperiod

Tricoire H , Møller M , Chemineau P , Malpaux B

Melatonin, which is synthesized at night by the pineal gland, is present in the cerebrospinal fluid (CSF), but its entry site and its role in this compartment are not known. Using several approaches, we tested the hypothesis that melatonin enters the CSF through the pineal recess, an evagination of the third ventricle. CSF melatonin concentrations are higher near the pineal gland than in the anterior part of the third ventricle, and decrease markedly (80%) after sealing of...

bp0009rdr9 | (1) | REDR1986

Spermatogenesis and Sertoli cell numbers and function in rams and bulls

Hochereau-de Reviers M. T. , Monet-Kuntz C. , Courot M.

Summary. The two main types of cellular associations (type I, 2 generations of spermatocytes + 1 of spermatids; type II, 1 of spermatocytes and 2 of spermatids) occupy, respectively, more than half and about a third of the seminiferous epithelium cycle in rams and bulls. However, the duration of the cycle of the seminiferous epithelium and that of spermatogenesis differ between the species. A1 spermatogonia and Sertoli cell total numbers are highly ...

bp0013cpr14 | Gamete Physiology | CPR1989

Maturation of pig oocytes in vivo and in vitro

Moor R. M. , Mattiolit M. , Ding J. , Nagai T.

Keywords: oocyte; maturation; meiosis; differentiation; fertilization; pig© 1990 Journals of Reproduction & Fertility Ltd...

bp0013cpr20 | Early Pregnancy | CPR1989

Regulation of uterine and conceptus secretory activity in the pig

Simmen R. C. M. , Simment R. C. M. ,

Summary. Evidence is presented for the involvement of a number of specific uterineand conceptus-derived proteins in endometrial differentiation and conceptus or feml development. These secretory proteins include mitogens (insulin-like growth factor-I and -II, epidermal growth factor, uterine lumina] fluid mitogen). binding and transport proteins (uteroferrin, insulin-like growth factor and retinal binding proteins, respectively), protease inhibitors (anti...