Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0017cpr12 | (1) | CPR2005

The use of microarrays to define functionally-related genes that are differentially expressed in the cycling pig uterus

Green J.A. , Kim J.G. , Whitworth J.G. , Agca C. , Prather R.S.

In swine and other livestock, the uterine endometrium exhibits dramatic morphological and secretory changes throughout the oestrous cycle and during pregnancy. Such physiological changes are a reflection of extremely complex interactions between gene products (RNA and protein). The recent development of genomics and proteomics methods, as well as associated bioinformatics tools, has provided the means to begin characterising such interactions. Indeed, the analysis of the...

bp0018cpr17 | Maturation of The Pre-ovulatory Follicle | CPR2009

Transcriptional, post-transcriptional and epigenetic control of porcine oocyte maturation and embryogenesis

Prather R.S. , Ross J.W. , Clay Isom S , Green J.A.

Embryogenesis is a complex process that is controlled at various levels. As new discoveries are made about molecular mechanisms that control development in other species, it is apparent that these same mechanisms regulate pig embryogenesis as well. Methylation of DNA and modification of histones regulate transcription, and mechanisms such as ubiquitinization, autophagy and microRNAs regulate development post-transcriptionally. Each of these systems of regulation is highl...