Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0017cpr3 | (1) | CPR2005

Gene expression in the brain-pituitary adipose tissue axis and luteinising hormone secretion during pubertal development in the gilt

Barb C. R. , Hausman G. J. , Rekaya R.

The occurrence of puberty in the female is due to the interplay of central and peripheral mechanisms in which the hypothalamic-pituitary-ovarian axis regulates growth and gonadal function, as well as adipocyte hormone secretion. Hypothalamic GnRH mRNA expression increased at 3.5 months of age and declined by 6 months of age. Concomitant with the age related reduction in the oestrogen negative feedback on LH secretion was a decline in hypothalamic oestrogen receptor-&alph...