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bp0002rdr20 | Oocyte Maturation | REDR1990

Derivation of pluripotent, embryonic cell lines from the pig and sheep

Notarianni Elena , Galli C , Laurie S , Moor RM , Evans MJ

Summary. As previously described for the establishment of stable, pluripotent cell lines from pig blastocysts, an analogous cell line was isolated from a sheep blastocyst. There are common features in the morphologies and growth characteristics of the pig and sheep cells in culture; in particular, pig and sheep cells display large nuclei and relatively sparse cytoplasm, as is observed in mouse embryonic stem cells. Furthermore, the morphology of the sheep cell...