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bp0005rdr34 | Ruminant Models for Human Clinical Medicine | REDR2002

The differential secretion of FSH and LH: regulation through genes, feedback and packaging

McNeilly AS , Crawford JL , Taragnat C , Nicol L , McNeilly JR

While the role of oestradiol and progesterone in the control of GnRH pulsatile secretion and generation of the preovulatory GnRH surge to induce release of the LH surge has been fully investigated, less attention has been given to changes in the pituitary gland that may sensitize gonadotrophs to switch from pulsatile release to surge release of LH, in particular. Furthermore, in the follicular phase while pulsatile secretion of LH is maximal, FSH secretion is reduced, yet both...