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bp0007rdr16 | Oocyte and Follicular Development in Ruminants | REDR2010

The earliest stages of follicular development: Follicle formation and activation

JE Fortune , Yang MY , Muruvi W

The formation of primordial follicles to establish a reservoir of resting follicles and the gradual depletion of that reservoir to provide a succession of growing follicles are key to female fertility, but little is known about the regulation of these early stages of follicular development. This review summarizes the efforts of our laboratory to elucidate these critical processes in cattle. Primordial follicles first appear in fetal ovaries around the end of the first trimeste...