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bp0008rdr19 | Male Function and Spermatogenesis | REDR2014

Potential and challenges of testis tissue xenografting from diverse ruminant species

Honaramooz Ali

Summary. In 2002, we reported that small fragments of testis tissue from immature mouse, pig or goat donors grafted in recipient mice undergo development, maturation and complete spermatogenesis, including the generation of fertilisation-competent murine, porcine or caprine sperm. Testis tissue xenografting (TTX) was then successfully applied using a range of donor species including laboratory/domestic/non-domestic animals and primates. This system offers a no...